Relative Bioefficiency via Simultaneous Regressions

Fits simultaneous regression models to compare two sources (reference and test) and estimates relative bioefficiency. Includes simultaneous exponential model with common asymptote (model = 1), slope-ratio model (model = 2), quadratic model (model = 3), linear-response plateau model (model = 4), and Michaelis-Menten model (model = 5). Output style follows the 'easyreg' package. Methods are based on Finney (1978, ISBN:0-85264-252-0), Mercer et al. (1978) , Robbins et al. (1979) , Noll et al. (1984) , Gallant and Fuller (1973) , Littell et al. (1997) , and Burnham and Anderson (2002, ISBN:978-0-387-95364-9).


Reference manual

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install.packages("BIOEFIC")

0.1.1 by Michel Blezins de Arruda, 5 months ago


Browse source code at https://github.com/cran/BIOEFIC


Authors: Michel Blezins de Arruda [aut, cre] (ORCID:


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports ggplot2, minpack.lm, stats

Suggests knitr, rmarkdown


See at CRAN