Mutational Signatures from COSMIC (Catalogue of Somatic Mutations in Cancer)

A data package with 2 main package variables: 'signature' and 'etiology'. The 'signature' variable contains the latest mutational signature profiles released on COSMIC < https://cancer.sanger.ac.uk/signatures/> for 3 mutation types: * Single base substitutions in the context of preceding and following bases, * Doublet base substitutions, and * Small insertions and deletions. 'cosmicsig' stands for COSMIC signatures. Please run ?'cosmicsig' for more information.

cosmicsig

Purpose

Mutational signatures data from COSMIC, the Catalogue Of Somatic Mutations In Cancer (https://cancer.sanger.ac.uk/signatures/). There are also some helper functions for handling COSMIC signatures.

Installation

Get the stable version

install.packages("cosmicsig")

Get the latest release

Install cosmicsig from GitHub:

if (!requireNamespace("remotes", quietly = TRUE)) {
  install.packages("remotes")
}
remotes::install_github(repo = "Rozen-Lab/cosmicsig", ref = "v1.3.0-branch")

Reference manual

https://github.com/Rozen-Lab/cosmicsig/blob/v1.3.0-branch/cosmicsig_1.3.0.pdf