A procedure that uses target-decoy competition (or knockoffs) to reject multiple hypotheses in the presence of group structure. The procedure controls the false discovery rate (FDR) at a user-specified threshold.
The groupwalk package contains the group-walk algorithm. Group-walk is a procedure that uses a target-decoy competition framework for rejecting multiple hypotheses when there is a presence of group structure. Group-walk controls the false discovery rate (FDR) at a user-specified threshold. Details regarding group-walk and its applications can be found here: https://www.biorxiv.org/content/10.1101/2022.01.30.478144v1
You can install the development version of groupwalk from GitHub with:
# install.packages("devtools")
devtools::install_github("freejstone/groupwalk")